Laurent Schoysman

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To date, the mutational status of EGFR and PTEN has been shown as relevant for favoring pro- or anti-tumor functions of STAT3 in human glioblastoma multiforme (GBM). We have screened genomic data from 154 patients and have identified a strong positive correlation between STAT3 and HDAC7 expression. In the current work we show the existence of a(More)
To evaluate imaging changes occurring in a rat model of elastase-induced abdominal aortic aneurysm (AAA), with emphasis on the intraluminal thrombus (ILT) occurrence. The post-induction growth of the AAA diameter was characterized using ultrasound in 22 rats. ILT was reported on 13 rats that underwent 14 magnetic resonance imaging (MRI) 2-18 days(More)
BACKGROUND Glioblastomas remain ominous tumors that almost invariably escape treatment. Connexins are a family of transmembrane, gap junction-forming proteins, some members of which were reported to act as tumor suppressors and to modulate cellular metabolism in response to cytotoxic stress. METHODS We analyzed the copy number and expression of the(More)
Technological innovations have endowed the development of powerful tools in medical imaging, such as transcranial color-coded sonography. In addition to other imaging techniques, its relevance in cerebrovascular disorders is increasing. This article aims to describe the technique through specification of its current indications in patients with arterial(More)
Plasmacytoma of the calvarium is very rare, accounting for the 0.7 % of all plasmacytomas [1–5]. The most common locations are the thoracic and lumbar spine (30–40 % of cases). Involvement of the hip, femurs, and ribs is less frequent [6]. Plasmacytoma of the calvarium can be indistinguishable from other lytic lesions, especially metastatic disease.(More)
Plasmacytoma of the calvarium is very rare, accounting for the 0.7 % of all plasmacytomas [1–5]. The most common locations are the thoracic and lumbar spine (30–40 % of cases). Involvement of the hip, femurs, and ribs is less frequent [6]. Plasmacytoma of the calvarium can be indistinguishable from other lytic lesions, especially metastatic disease.(More)
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