Laurent P. Ferrier

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BACKGROUND AND AIMS Intestinal barrier impairment is incriminated in the pathophysiology of intestinal gut disorders associated with psychiatric comorbidity. Increased intestinal permeability associated with upload of lipopolysaccharides (LPS) translocation induces depressive symptoms. Gut microbiota and probiotics alter behavior and brain neurochemistry.(More)
1. Effects of oestrogen on the current evoked by ATP and benzoylbenzoyl ATP (BzATP) in CV-1 monkey kidney cells transformed by SV 40 (COS cells) expressing the human P2X7 (hP2X7) purinoceptor were studied using standard patch-clamp techniques. 2. 17beta-Oestradiol rapidly and reversibly inhibited the whole-cell hP2X7 receptor cation current. This inhibitory(More)
Neonatal stress is known to alter immune responses in adults and parasitic infection is modulated by the immune status of the host. The present study aimed to establish whether neonatal maternal deprivation affects the time course of Nippostrongylus brasiliensis infection and associated intestinal alterations in adult rats. Rat pups were separated from(More)
Recent results from Cannon, Hayes, and Tipper (2010) have established that the Action Compatibility Effect (ACE) is hedonically marked and elicits a genuine positive reaction. In this work, we aim to show that the hedonic marking of the ACE has incidental consequences on affective judgment. For this, we used the affective priming paradigm principle (for a(More)
Peptide YY (PYY) is involved in the regulation of several gastro-intestinal functions, including motility. The aims of the present study were (i) to characterize the effects of PYY on smooth muscle strips obtained from the different gastro-intestinal segments in rats and in humans and (ii) to realize a map of the Y receptors expression. Contractions of(More)
OBJECTIVE Intestinal proteases carry out a variety of functions in the gastrointestinal (GI) tract. Studies have reported that elevated enteric proteases in patients with GI disease can alter intestinal physiology, however the origin (human vs. microbial) of elevated proteases in patients with GI disease is unclear. AIM The aim of this study was to(More)
The Simon effect usually refers to the observation that responding to a nonspatial feature of a stimulus is faster when the position of the stimulus (task-irrelevant) matches the position of the to-be-executed response. The Simon effect can disappear when the Simon task is preceded by a spatial compatibility task with an incompatible mapping. In this(More)
Currently, a growing body of studies demonstrates memory-perception interactions (see Barsalou, 2008; Heurley et al., 2012; Lobel, 2014, for reviews). Even if such interactions are highly relevant to support embodied approaches of cog-nition as well as to better understand memory and perception (e. functional role remains unclear: Why would perception(More)
This study explores the influence of typical size during a categorization task. The specificity of this experimental work is based on the homogeneity of the graphic stimuli size. We have created a typical size standard of our stimuli, that concerns the real size of the objects represented by the drawings of homogeneous sizes. Then, a priming experiment was(More)
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