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The role of the centrosomes in microtubule nucleation remains largely unknown at the molecular level. ␥-Tubulin and the two associated proteins h103p (hGCP2) and h104p (hGCP3) are essential. These proteins are also present in soluble complexes containing additional polypeptides. Partial sequencing of a 76-kD polypeptide band from these complexes allowed the(More)
The role of the centrosomes in microtubule nucleation remains largely unknown at the molecular level. ␥-Tubulin and the two associated proteins h103p (hGCP2) and h104p (hGCP3) are essential. These proteins are also present in soluble complexes containing additional polypeptides. Partial sequencing of a 76-kD polypeptide band from these complexes allowed the(More)
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