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  • Anne Puel, Rainer Döffinger, +26 authors Jean-Laurent Casanova
  • Medicine
  • The Journal of experimental medicine
  • 2010 (First Publication: 15 February 2010)
  • Most patients with autoimmune polyendocrine syndrome type I (APS-I) display chronic mucocutaneous candidiasis (CMC). We hypothesized that this CMC might result from autoimmunity to interleukinContinue Reading
  • Jean-Laurent Casanova, Laurent Abel, Lluís Quintana-Murci
  • Biology, Medicine
  • Annual review of immunology
  • 2011 (First Publication: 23 April 2011)
  • Toll-like receptors (TLRs) and interleukin-1 receptors (IL-1Rs) have TIR intracellular domains that engage two main signaling pathways, via the TIR-containing adaptors MyD88 (which is not used byContinue Reading
  • Laure Gineau, Céline Cognet, +17 authors Emmanuelle Jouanguy
  • Biology, Medicine
  • The Journal of clinical investigation
  • 2012 (First Publication: 1 March 2012)
  • Natural killer (NK) cells are circulating cytotoxic lymphocytes that exert potent and nonredundant antiviral activity and antitumoral activity in the mouse; however, their function in host defense inContinue Reading