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BACKGROUND Several studies have suggested that the respiratory muscles are weak in patients with heart failure, but the aetiology and clinical relevance of this weakness are unclear. In order to see if respiratory muscle weakness in this context is part of a more generalised myopathic process, respiratory and limb muscle strength were compared in patients(More)
BACKGROUND There is increasing appreciation of gender differences in COPD but scant data whether risk factors for low lung function differ in men and women. We analysed data from 3 years follow-up in 178 women and 464 men with COPD, participants in the Euroscop Study who were smokers unexposed to inhaled corticosteroids. METHODS Explanatory variables of(More)
Vital capacity (VC) and maximum mouth pressures are often used to monitor respiratory function in motor neuron disease (MND), but require the use of a mouthpiece. Sniff nasal inspiratory pressure (SNIP) is a simple and reliable means of measuring inspiratory muscle strength; it does not involve the use of a mouthpiece and might therefore be better than VC(More)
BACKGROUND Little is known about the long term effects of anterior spinal surgery on pulmonary function in adult patients with idiopathic scoliosis. A study was therefore undertaken of pulmonary function before and after anterior spinal surgery in this group of patients. METHODS Fourteen patients (12 women) of mean age 26.5 years (range 17-50, 10 > or =(More)
PURPOSE We describe our pilot experience with percutaneous cryoablation of renal masses using real-time sonography. MATERIALS AND METHODS Three patients presented with 4 renal masses in 4 kidneys, which enhanced with contrast administration by computerized tomography or magnetic resonance imaging criteria. Renal neoplasm cryoablation was performed using(More)
Respiratory function was assessed in 20 patients with idiopathic scoliosis undergoing spinal surgery (median age, 15 years; range, 11-34 years; median preoperative vital capacity, 67%; range, 28-109% predicted). Ten patients underwent anterior spinal surgery through a thoracotomy incision, seven of whom had posterior spinal surgery as a second-stage(More)
Although chronic obstructive pulmonary disease (COPD) patients frequently report symptoms, it is not known which factors determine the course of symptoms over time and if these differ according to the sex of the patient. The current study investigated predictors for presence, development and remission of COPD symptoms in 816 males and 312 females completing(More)
BACKGROUND Transdiaphragmatic pressure (sniff PDI) during maximal sniffs is a useful clinical test of inspiratory muscle function. Although a normal range has been established for sniff PDI using air filled balloons, no comparable data are available for catheter mounted pressure transducers. METHODS Using a single catheter with two pressure transducers 15(More)
BACKGROUND The pathogenesis of dyspnoea in patients with chronic heart failure is poorly understood. Static lung compliance is reduced in chronic heart failure. The relation between static lung compliance and exercise capacity and dyspnoea in chronic heart failure has been investigated. METHODS Static lung compliance was calculated from expiratory(More)
The cause of the breathlessness and reduced exercise capacity that occur in patients with chronic heart failure remains obscure. We examined the hypothesis that airway obstruction and bronchial hyper-responsiveness, which are recognised features of chronic heart failure, might contribute to the breathlessness and reduced exercise capacity in this condition.(More)