Laurence Blatt

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TRANSITION FROM SMALL CELL TO NON-SMALL CELL LUNG CARCINOMA CELL PHENOTYPE INDUCED BY OVEREXPRESSION OF MYC AND RAS ONCOGENES. J. Adamkiewicz In clinical practice small cell lung carcinoma (SCLC) frequently exhibit more than one histologic pattern. Thus, ceils with SCLC and non-small cell lung carcinoma (NSCLC) histologies appear in the same SCLC tumor, and(More)
Blatt, L. (University of Wisconsin, Madison), F. E. Dorer, and H. J. Sallach. Occurrence of hydroxypyruvate-l-glutamate transaminase in Escherichia coli and its separation from hydroxypyruvate-phosphate-l-glutamate transaminase. J. Bacteriol. 92:668-675. 1966.-The formation of l-serine from hydroxypyruvate by a transamination reaction with l-glutamate has(More)
Ribavirin and 2'-O-methylcytidine 5'-phosphoramidates derived from L-alanine methyl ester bearing either an O-phenyl or a biodegradable O-[3-(acetyloxy)-2,2-bis(ethoxycarbonyl)propyl] or O-[3-(acetyloxymethoxy)-2,2-bis(ethoxycarbonyl)propyl] protecting group were prepared. The kinetics of the deprotection of these pro-drugs by porcine liver esterase and by(More)
Interferon-consensus 1 (IFN-Con 1) is a novel synthetic protein generated from codons for the most frequent amino acids in different type 1 IFNs. Compared with natural IFNs, IFN-Con 1 has been shown to have higher specific activity and antiproliferative activity and a higher ability to induce natural killer cells. In this study, the effects of IFN-Con 1(More)
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