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OBJECTIVES To evaluate the effectiveness of aviation-style teamwork training in improving operating theatre team performance and clinical outcomes. SETTING 3 operating theatres in a UK district general hospital, 1 acting as a control group and the other 2 as the intervention group. PARTICIPANTS 72 operations (37 intervention, 35 control) were observed(More)
OBJECTIVE To investigate the fetal angiotensin II type 1 receptor genotype in pre-eclampsia. DESIGN Case-control study. POPULATION Forty-one maternal-fetal pairs from pre-eclamptic pregnancies and 80 maternal-fetal pairs from normotensive pregnancies. METHODS Maternal and fetal DNA was genotyped at three diallelic polymorphisms, at nucleotides 573,(More)
OBJECTIVES To develop a sensitive, reliable tool for enumerating and evaluating technical process imperfections during surgical operations. DESIGN Prospective cohort study with direct observation. SETTING Operating theatres on five sites in three National Health Service Trusts. PARTICIPANTS Staff taking part in elective and emergency surgical(More)
BACKGROUND We previously developed and validated the Oxford NOTECHS rating system for evaluating the non-technical skills of an entire operating theatre team. Experience with the scale identified the need for greater discrimination between levels of performance within the normal range. We report here the development of a modified scale (Oxford NOTECHS II)(More)
Birthweight predicts health later in life and is influenced by inherited factors. We investigated the association of the c.61G > A, and c.2566G > A polymorphisms in the epidermal growth factor (EGF) gene [GenBank NM_001963] with birthweight in three groups of healthy pregnant women, and in women with pregnancies affected by fetal growth restriction (FGR).(More)
BACKGROUND Recognising the limitations of a paper-based approach to documenting vital sign observations and responding to national clinical guidelines, we have explored the use of an electronic solution that could improve the quality and safety of patient care. We have developed a system for recording vital sign observations at the bedside, automatically(More)
There is biochemical and animal model evidence supporting a pathological role of the ACT gene in AD. However, direct genetic evidence remains controversial and has been mostly limited to individual single nucleotide polymorphism (SNP) analysis. To resolve this apparent conflict we have used a high-density ACT SNP map, constructed haplotypes and explored(More)
OBJECTIVES To examine the effectiveness of a "systems" approach using Lean methodology to improve surgical care, as part of a programme of studies investigating possible synergy between improvement approaches. SETTING A controlled before-after study using the orthopaedic trauma theatre of a UK Trust hospital as the active site and an elective orthopaedic(More)
BACKGROUND To investigate the effectiveness of combining teamwork training and lean process improvement, two distinct approaches to improving surgical safety. We conducted a controlled interrupted time series study in a specialist UK Orthopaedic hospital incorporating a plastic surgery team (which received the intervention) and an Orthopaedic theatre team(More)