Laura W. Y. Lo

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Hypoxia induces endothelial dysfunction that results in a series of cardiovascular injuries. Early growth response-1 (Egr-1) has been indicated as a common theme in vascular injury. Here we demonstrates that in bovine aortic endothelial cells (ECs) subjected to hypoxia (PO(2) approximately 23 mmHg), rapidly increased Egr-1 mRNA expression which peaked(More)
Endothelial cells (ECs) subjected to shear stress constantly release nitric oxide (NO). The effect of NO on shear stress-induced endothelial responses was examined. ECs subjected to shear stress induced a transient and shear force-dependent increase in early growth response-1 (Egr-1) mRNA levels. Treatment of ECs with an NO donor,(More)
1. Introduction The goal of the 3D Icons project, funded under the European Commission's ICT Policy Support Program which builds on the results of CARARE 1 and 3D-COFORM 2 , is to provide Europeana with 3D models of architectural and archaeological monuments of remarkable cultural importance. The project will end in February 2015, bringing together 16(More)
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