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  • Laura T Letendre, Ronald K. Tessman, Scott R. McClure, Valerie Kvaternick, James B. Fischer, Peter D. Hanson
  • Biology, Medicine
  • American journal of veterinary research
  • 1 November 2008
  • OBJECTIVE To determine pharmacokinetic parameters and variables, firocoxib concentrations in urine and plasma, urine-to-plasma ratios, and the urine depletion profile of firocoxib and to evaluateContinue Reading
  • Laura T Letendre, Mark F. Scott, G Dobson, Ismael J. Hidalgo, Bruce Aungst
  • Chemistry, Medicine
  • Pharmaceutical Research
  • 1 August 2004
  • AbstractPurpose.The purpose of this study was to develop and validate a method for separately evaluating the roles of gastrointestinal absorption and hepatic extraction as barriers to oralContinue Reading
    The pharmacokinetics of afoxolaner and milbemycin oxime (A3 and A4 forms) in dogs were evaluated following the oral administration of NexGard Spectra® (Merial), a fixed combination chewableContinue Reading