Laura O'Neill

Learn More
Chronic Obstructive Pulmonary Disease (COPD) is an inflammatory process of the lung inducing persistent airflow limitation. Extensive systemic effects, such as skeletal muscle dysfunction, often characterize these patients and severely limit life expectancy. Despite considerable research efforts, the molecular basis of muscle degeneration in COPD is still a(More)
  • Joanne Miles, Jennifer A. Mitchell, Lyubomira Chakalova, Beatriz Goyenechea, Cameron S. Osborne, Laura O'Neill +3 others
  • 2007
Several lines of evidence have established strong links between transcriptional activity and specific post-translation modifications of histones. Here we show using RNA FISH that in erythroid cells, intergenic transcription in the human beta-globin locus occurs over a region of greater than 250 kb including several genes in the nearby olfactory receptor(More)
  • 1