Laura Nyawira Wangai

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Plasmodium falciparum resistance to chloroquine (CQ) denied healthcare providers access to a cheap and effective anti-malarial drug. Resistance has been proven to be due to point mutations on the parasite’s pfcrt gene, particularly on codon 76, resulting in an amino acid change from lysine to threonine. This study sought to determine the prevalence of the(More)
Detection of Plasmodium species by microscopy has been the gold standard for diagnosis of malaria for more than a century. Despite the fact that there is a significant decline in the number of positive cases reported from microscopy, antimalarial drugs prescriptions are on continuous increase as patients present with symptoms of malaria. This makes it(More)
The present study was performed to determine the optimal dose of alloxan monohydrate required to induce diabetes in male BALB/c mice and investigatein vivo hypoglycemic activity of aqueous and ethylacetate leaf and stem bark extracts of Pappea capensisLin alloxanized diabetic BALB/c mice.In addition, the proximate composition of P. capensis powder was(More)
BACKGROUND Poliomyelitis is an acute viral infection caused by poliovirus and transmitted via the fecal-oral route. The causative agent is one of the three serotypes of poliovirus (serotypes 1, 2, 3) that differ slightly in capsid protein. Prolonged vaccine-related poliovirus shedding in human immunodeficiency virus (HIV) positive individuals has been(More)
BACKGROUND Injection drug use is steadily rising in Kenya. We assessed the prevalence of both human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) infections among injecting heroin users (IHUs) at the Kenyan Coast. METHODS A total of 186 IHUs (mean age, 33 years) from the Omari rehabilitation center program in Malindi were consented and(More)
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