Laura Napolitano

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Patients with the acquired immunodeficiency syndrome are at risk to develop a variety of different cancers. Based on epidemiológica! data, Kaposi's sarcoma and non-Hodgkin's lymphoma have been clearly asso ciated with infection by the human immunodeficiency virus (HIV). Ad ditional cancers such as basal cell and squamous cell carcinomas, mela noma, and(More)
BACKGROUND The introduction of C-C chemokine receptor type-5 (CCR5) antagonists as antiretroviral therapy has led to the need to study HIV co-receptor tropism in different HIV-1 subtypes and geographical locations. This study was undertaken to evaluate HIV-1 co-receptor tropism in the developing world where non-B subtypes predominate, in order to assess the(More)
In this paper we investigate the impact of patient's profile on the usability of filling clinical questionnaires on smart devices. Our study was conducted in an oncological day hospital, where the EORTC QLQ-C30 quality of life questionnaire is administered to outpatients using computerized devices (smartphone, tablet, and laptop) and a paper form. We show(More)
BACKGROUND During the first two decades of the U.S. AIDS epidemic, and unlike some malignancies, breast cancer risk was significantly lower for women with human immunodeficiency virus (HIV) infection compared to the general population. This deficit in HIV-associated breast cancer could not be attributed to differences in survival, immune deficiency,(More)
Accurate co-receptor tropism (CRT) determination is critical for making treatment decisions in HIV management. We created a genotypic tropism prediction tool by utilizing the case-based reasoning (CBR) technique that attempts to solve new problems through applying the solution from similar past problems. V3 loop sequences from 732 clinical samples with(More)
L’inappropriatezza dei test diagnostici è un problema reale in Medicina di Laboratorio con forti risvolti di tipo etico, di malasanità, di risk management e di costi. Il Laboratorio di analisi non deve essere considerato semplicemente un servizio a disposizione dei reparti, un centro di produzione di numeri. Il ruolo di un moderno Laboratorio clinico è(More)
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