Laura Löffler

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To develop a model of heart muscle, we studied cat papillary muscle contracting in a quasi-isometric condition under a fixed inotropic state. The properties of resting muscle were determined by using a step stretch of less than 1.2% of Lmax for initial lengths from 85 to 100% Lmax. The passive force response suggested the model of the passive branch (Fig.(More)
The mechanism of injury and death of muscle cells in the inflammatory myopathies (dermatomyositis, polymyositis, and inclusion body myositis) remains obscure. We and others have not detected apoptosis in the muscle biopsies from patients with myositis despite clear evidence of cell damage and loss. We provide evidence in this study that Fas ligand (FasL) as(More)
A radioimmunoassay procedure has been developed for the direct measurement of methotrexate (MTX) in plasma, serum, cerebrospinal fluid, or urine samples. The assay is sensitive to levels of at least 100 pg of MTX and is highly specific for MTX in the presence of folinic acid (citrovorum factor), folic acid, tetrahydrogolic acid, and other folate analogs and(More)
Arbeitskreise Im Bereich der Arbeitskreise gibt es neue Impulse: Der Arbeitskreis " Natürlichsprachige Anforderungen " wurde neu gegründet, und die Arbeitskreise " Softskills Required " sowie " RE und eingebettete Systeme " sollen wieder neu aufleben. Nähere Informationen hierzu finden Sie auf unserer Fachgruppen-Webseite (siehe unten).
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