Laura Hill

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BACKGROUND There is no method routinely used to predict response to anthracycline and cyclophosphamide-based chemotherapy in the clinic; therefore patients often receive treatment for breast cancer with no benefit. Loss of the Fanconi anemia/BRCA (FA/BRCA) DNA damage response (DDR) pathway occurs in approximately 25% of breast cancer patients through(More)
Software engineering education for working professionals remains a challenge from the perspective of determining relevant content; identifying effective methods for delivery; and maintaining the focus and motivation of students. This panel brings together academic and industry professionals to share their perspectives and experiences. Anticipated points for(More)
Sixty adults (ages 19 to 80) were divided into three age groups. Each individual completed the Problem Solving Inventory (PSI), which assesses an individual's self-perception of problem-solving ability, prior to completing two types of problems, including concept-identification tasks and six everyday, practical problems. When the level of education across(More)
BACKGROUND Atrial fibrillation is associated with higher mortality. Identification of causes of death and contemporary risk factors for all-cause mortality may guide interventions. METHODS AND RESULTS In the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial(More)
Anorexia nervosa (AN) is a severe and debilitating disorder with significant medical and psychological sequelae. To date, there are no effective treatments for adults, resulting in high rates of chronicity, morbidity, and mortality. Recent advances in brain imaging research have led to an improved understanding of etiology and specific neurobiological(More)
Evidence suggests that weight suppression, the difference between an individual's highest historical body weight and current body weight, may play a role in the etiology and/or maintenance of eating disorders (EDs), and may also impact ED treatment. However, there are limited findings regarding the association between weight suppression and dimensions of ED(More)
OBJECTIVE Health-related quality of life (HRQoL) is an emerging area of research in eating disorders (EDs) that has not been examined in adolescents in detail. The aim of the current study is to investigate HRQoL in an adolescent ED sample, examining the impact of ED symptoms on HRQoL. METHODS Sixty-seven treatment-seeking adolescents (57 females) with(More)
Previous literature suggests that women evidence more bilateral cerebral organization, particularly in language processing, whereas men show greater left hemisphere dominance for language. This study examined the magnitude of these gender differences in a lateralized lexical decision task and the implications of such differences to semantic processing and(More)
One of the claimed advantages of object-oriented (OO) development is that developers can use objects in a uniform modeling approach throughout the process. In particular, they can coherently apply the same notation for representing these objects and their relations in both analysis and design. Given this, the claims by many OO methodologists (see, e.g., [1,(More)