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  • Jesus M. Banales, Vincenzo Cardinale, +21 authors Domenico Alvaro
  • Medicine
  • Nature Reviews Gastroenterology &Hepatology
  • 2016 (First Publication: 1 May 2016)
  • Cholangiocarcinoma (CCA) is a heterogeneous group of malignancies with features of biliary tract differentiation. CCA is the second most common primary liver tumour and the incidence is increasingContinue Reading
  • Javier Vaquero, Nathalie Guedj, Audrey Clapéron, Thanh Huong Nguyen Ho-Bouldoires, Valérie Paradis, Laura Fouassier
  • Medicine
  • Journal of hepatology
  • 2017 (First Publication: 1 February 2017)
  • Cholangiocarcinoma (CCA) is an aggressive tumor with a poor prognosis due to its late clinical presentation and the lack of effective non-surgical therapies. Unfortunately, most of the patients areContinue Reading
  • Audrey Clapéron, Martine Mergey, +9 authors Laura Fouassier
  • Medicine, Biology
  • Journal of hepatology
  • 2014 (First Publication: 1 August 2014)
  • BACKGROUND & AIMS Epithelial-mesenchymal transition (EMT) is a cellular process involved in cancer progression. The first step of EMT consists in the disruption of E-cadherin-mediated adherensContinue Reading
  • Ariane Mallat, Laura Fouassier, +7 authors Sophie Lotersztajn
  • Biology, Medicine
  • The Journal of clinical investigation
  • 1995 (First Publication: 1 July 1995)
  • Ito cells play a pivotal role in the development of liver fibrosis associated with chronic liver diseases. During this process, Ito cells acquire myofibroblastic features, proliferate, and synthesizeContinue Reading
  • Thanh Huong Nguyen Ho-Bouldoires, Audrey Clapéron, +11 authors Laura Fouassier
  • Chemistry, Medicine
  • Free radical biology & medicine
  • 2015 (First Publication: 1 December 2015)
  • The development and progression of liver cancer are characterized by increased levels of reactive oxygen species (ROS). ROS-induced oxidative stress impairs cell proliferation and ultimately leads toContinue Reading
  • P L Tharaux, Christos Chatziantoniou, Daniel Casellas, Laura Fouassier, Raymond Ardaillou, J C Dussaule
  • Medicine
  • Circulation
  • 1999 (First Publication: 27 April 1999)
  • BACKGROUND The progression of hypertension during NO deficiency is associated with renal vascular fibrosis due to increased extracellular matrix (mainly collagen I) formation. The purpose of theContinue Reading
  • Jesús Vaquero, Thanh Huong Nguyen Ho‐Bouldoires, Audrey Clapéron, Laura Fouassier
  • Medicine, Biology
  • Oncogene
  • 2017 (First Publication: 1 June 2017)
  • The transmission of cellular information requires fine and subtle regulation of proteins that need to interact in a coordinated and specific way to form efficient signaling networks. The spatial andContinue Reading