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- F T Farrell, L E Jones
- Proceedings of the National Academy of Sciencesā¦
- 1986

Among other results, we rationally calculate the algebraic K-theory of any discrete cocompact subgroup of a Lie group G, where G is either O(n, 1), U(n, 1), Sp(n, 1), or F(4), in terms of the homology of the double coset space Gamma\G/K, where K is a maximal cocompact subgroup of G. We obtain the formula K(n)(ZGamma) [unk] [unk] congruent with [unk](i=0)ā¦ (More)

Ecological and evolutionary dynamics can occur on similar timescales. However, theoretical predictions of how rapid evolution can affect ecological dynamics are inconclusive and often depend on untested model assumptions. Here we report that rapid prey evolution in response to oscillating predator density affects predator-prey (rotifer-algal) cycles inā¦ (More)

- Laura E Jones, Stephen P Ellner
- Journal of mathematical biology
- 2007

We study the qualitative properties of population cycles in a predator-prey system where genetic variability allows contemporary rapid evolution of the prey. Previous numerical studies have found that prey evolution in response to changing predation risk can have major quantitative and qualitative effects on predator-prey cycles, including: (1) largeā¦ (More)

- F. T. FARRELL, L. E. JONES
- 2007

Three types of manifolds, spherical, fiat, and hyperbolic, are paradigms of geometric behavior. These are the Riemannian manifolds of constant positive, zero, and negative sectional curvatures, respectively. (The positive and negative sectional curvatures may be assumed, after scaling, to be + 1 and -1.) There is an equivalent synthetic geometric definitionā¦ (More)

- Peter B McIntyre, Laura E Jones, Alexander S Flecker, Michael J Vanni
- Proceedings of the National Academy of Sciencesā¦
- 2007

There is increasing evidence that species extinctions jeopardize the functioning of ecosystems. Overfishing and other human influences are reducing the diversity and abundance of fish worldwide, but the ecosystem-level consequences of these changes have not been assessed quantitatively. Recycling of nutrients is one important ecosystem process that isā¦ (More)

- Scott Davis, Stephanie Propp, +7 authors Christine Esau
- Nucleic acids research
- 2009

Chemically modified antisense oligonucleotides (ASOs) are widely used as a tool to functionalize microRNAs (miRNAs). Reduction of miRNA level after ASO inhibition is commonly reported to show efficacy. Whether this is the most relevant endpoint for measuring miRNA inhibition has not been adequately addressed in the field although it has importantā¦ (More)

- Lutz Becks, Stephen P Ellner, Laura E Jones, Nelson G Hairston
- Ecology letters
- 2010

Adaptive variation in the traits determining ecological interactions can lead to evolution so rapid that ecological dynamics change course while in progress (i.e., 'eco-evolutionary dynamics'). However, little is known about how the qualitative properties of eco-evolutionary dynamics (e.g., cycling, equilibrium, etc.) are affected by the amount of heritableā¦ (More)

- Laura E Jones, Alan S Perelson
- Bulletin of mathematical biology
- 2005

When highly active antiretroviral therapy is administered for long periods of time to HIV-1 infected patients, most patients achieve viral loads that are "undetectable" by standard assay (i.e., HIV -1 RNA<50 copies/ml). Yet despite exhibiting sustained viral loads below the level of detection, a number of these patients experience unexplained episodes ofā¦ (More)

- Laura E Jones, Lutz Becks, Stephen P Ellner, Nelson G Hairston, Takehito Yoshida, Gregor F Fussmann
- Philosophical transactions of the Royal Societyā¦
- 2009

Character evolution that affects ecological community interactions often occurs contemporaneously with temporal changes in population size, potentially altering the very nature of those dynamics. Such eco-evolutionary processes may be most readily explored in systems with short generations and simple genetics. Asexual and cyclically parthenogeneticā¦ (More)

Despite progress in the past decade, researchers struggle to evaluate the hypothesis that environmental conditions compromise immunity and facilitate new disease outbreaks. In this chapter, we review known immunological mechanisms for selected phyla and find that there are critical response pathways common to all invertebrates. These include theā¦ (More)