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A novel genome-wide screen that combines patient outcome analysis with array comparative genomic hybridization and mRNA expression profiling was developed to identify genes with copy number alterations, aberrant mRNA expression, and relevance to survival in glioblastoma. The method led to the discovery of physical gene clusters within the cancer genome with(More)
OBJECTIVE The present study developed the Weight Bias Internalization Scale (WBIS), an 11-item measure assessing internalized weight bias among the overweight and obese. METHODS AND PROCEDURES An Internet sample was recruited through online community discussion groups and snowball sampling via e-mail. Women (n = 164) and men (n = 34) with a BMI > 25 kg/m2(More)
Glioblastoma is classified into two subtypes on the basis of clinical history: "primary glioblastoma" arising de novo without detectable antecedent disease and "secondary glioblastoma" evolving from a low-grade astrocytoma. Despite their distinctive clinical courses, they arrive at an indistinguishable clinical and pathologic end point highlighted by(More)
OBJECTIVE To compare the strength of weight bias to other common biases, and to develop a psychometrically sound measure to assess and compare bias against different targets. SUBJECTS A total of 368 university students (75.4% women, 47.6% white, mean age: 21.53 years, mean body mass index (BMI): 23.01 kg/m(2)). MEASUREMENTS A measure was developed to(More)
Lesbian, gay, and bisexual (LGB) individuals suffer serious mental health disparities relative to their heterosexual peers, and researchers have linked these disparities to difficult social experiences (e.g., antigay victimization) and internalized biases (e.g., internalized homophobia) that arouse stress. A recent and growing body of evidence suggests that(More)
The present study sought to identify patterns and predictors of disclosure of sexual orientation to healthcare providers among lesbian, gay, and bisexual (LGB) adults. METHODS Respondents were 396 self-identified LGB individuals ages 18-59, recruited from diverse community venues in New York City, with equal numbers of men and women and Whites, Blacks,(More)
Obesity is a major health concern for a large proportion of the population, yet many obese individuals do not receive weight loss treatment. The present study investigated weight-loss treatment seeking and barriers that may prevent treatment seeking. A community sample of overweight or obese participants (N=154; Mean BMI=33.3 kg/m2) completed an Internet(More)
OBJECTIVE The present study examined the relationship between experiences of discrimination and occurrence of binge eating among overweight and obese persons, a population which has previously shown elevated rates of binge eating. METHODS Internet-based questionnaires were used to measure frequency and impact of discrimination, binge eating frequency, and(More)
OBJECTIVE Widespread bias against obese individuals may lead to the internalization of weight bias in obese persons. This study examined correlates of internalized weight bias (IWB) in obese patients with binge eating disorder (BED). METHOD One hundred treatment-seeking obese patients with BED were administered with the eating disorders examination(More)
BACKGROUND Weight bias is widespread and has numerous harmful consequences. The internalization of weight bias has been associated with significant psychological impairment. Other forms of discrimination, such as racial and anti-gay bias, have been shown to be associated with physical health impairment. However, research has not yet examined whether(More)