Laura De Miguel

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Patients with the autoimmune rheumatic disease systemic lupus erythematosus (SLE) have multiple defects in lymphocyte signaling and function that contribute to disease pathogenesis. Such defects could be attributed to alterations in metabolic processes, including abnormal control of lipid biosynthesis pathways. Here, we reveal that CD4+ T cells from SLE(More)
To review our experience over 10 years in endoscopic resection of third ventricular colloid cysts, describing the details of the transventricular–transchoroidal approach used in selected patients. This series included 24 patients with colloid cysts of the third ventricle treated in our department between October 2001 and January 2013 using an endoscopic(More)
Membrane lipid microdomains (lipid rafts) play an important role in T cell function by forming areas of high lipid order that facilitate activation. However, their role in regulating T cell differentiation and function remains controversial. In this study, by applying a new approach involving microscopy and flow cytometry, we characterize membrane lipid(More)
Based on the definition of admissible order for interval-valued Atanassov intuitionistic fuzzy sets, we study OWA operators in these sets distinguishing between the weights associated to the membership and those associated to the nonmembership degree which may differ from the latter. We also study Choquet integrals for aggregating information which is(More)
In this work, we introduce a new class of functions defined on the interval-valued setting. These functions extend classical OWA operators but allow for different weighting vectors to handle the lower bounds and the upper bounds of the considered intervals. As a consequence, the resulting functions need not be an interval-valued aggregation function, so we(More)