Laura Cappelletti

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Francesca Elli2
Paola Ciceri2
Mario Cozzolino2
Gaetano Bulfamante2
Delfina Tosi2
2Francesca Elli
2Paola Ciceri
2Mario Cozzolino
2Gaetano Bulfamante
2Delfina Tosi
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Osteonectin, also termed SPARC, is a noncollagenous protein of bone matrix. Since there are controversial results regarding its role during the process of vascular calcification, we investigated osteonectin expression in our in vitro calcification model. Rat vascular smooth muscle cells (VSMCs) were challenged with high phosphate (5 mmol/L Pi) and analyzed(More)
An increasing amount of patients affected by advanced chronic kidney disease suffer from vascular calcification (VC) that associates with cardiovascular morbidity and mortality. In this study, we created a new experimental in vitro model, trying to better elucidate high phosphate (Pi)-induced VC pathogenic mechanisms. Rat aortic vascular smooth muscle cells(More)
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