Laura A. van de Pol

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Our aim was to compare the predictive accuracy of 4 different medial temporal lobe measurements for Alzheimer's disease (AD) in subjects with mild cognitive impairment (MCI). Manual hippocampal measurement, automated atlas-based hippocampal measurement, a visual rating scale (MTA-score), and lateral ventricle measurement were compared. Predictive accuracy(More)
abstraCt Aim To investigate the degree of medial temporal lobe atrophy (MTA) and white matter hyperintensities (WMH) on MRI, in clinical subtypes of MCI. Methods Consecutive non­demented subjects older than 55 years (n = 329) with an aver­ age age of 69 ± 8 years (mean ± SD) and MMSE score of 28 ± 2 were recruited from memory clinics of multiple centres.(More)
Atrophy of medial temporal lobes on MRI in " probable " Alzheimer's disease and normal ageing: diagnostic value and neuropsychological correlates ask after 20 years of visual rating of medial temporal lobe atrophy on MRI in dementia, what have we learnt? HISTORICAL PERSPECTIVE In the last decades of the previous century, interest in diagnosing Alzheimer's(More)
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