Laura A Wakely

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AIMS To determine the effects of argon green panretinal laser photocoagulation on retinal nerve fibre layer thickness, threshold visual fields, and Estermann full-binocular visual fields over time in diabetic retinopathy. METHOD Prospective, pilot clinical study. Time-domain optical coherence tomography (TD-OCT) of the optic nerve head and 24-2 SITA-Fast(More)
BACKGROUND/AIMS To compare several methods of macular hole measurement using optical coherence tomography (OCT), and to assess their predictive capability against anatomical and visual outcomes in a single cohort of patients. METHODS A retrospective study of 50 eyes undergoing standardised macular hole surgery. All patients underwent preoperative OCT(More)
PURPOSE To assess the effect on intraocular pressure (IOP) of varying the length of the side incisions of the scleral flap during trabeculectomy. MATERIALS AND METHODS Trabeculectomy operations were performed with adjustable sutures on 8 donor human eyes connected to a constant flow infusion with real-time IOP monitoring, using either a large (4 x 4 mm,(More)
Recent developments in the miniaturization of confocal imaging technology have resulted in the development of a hand-held confocal microscope probe. There are many structures of interest in the human eye that are within reach of a fluorescence-mode confocal microscope; this study assessed the feasibility of in vivo human ocular imaging. Safety analysis was(More)
BACKGROUND AND OBJECTIVE The miniaturization of confocal imaging technology has resulted in the development of a handheld confocal microscope probe capable of fluorescence mode imaging. Findings in the subepithelial tissues of glaucoma filtering blebs using this novel approach for proof of concept are described. PATIENTS AND METHODS A fiberoptic confocal(More)
BACKGROUND To investigate the effect of adding indocyanine green to mitomycin C in augmented trabeculectomy. DESIGN A prospective, non-comparative interventional case series. PARTICIPANTS A total of 37 eyes of 37 patients followed up for 1 year. METHODS A solution containing 12.5 mg/mL of indocyanine green was added to mitomycin C, resulting in an(More)
BACKGROUND To assess the efficacy of Celecoxib, a cyclo-oxygenase 2 (COX-2) inhibitor, as prophylaxis for cystoid macular oedema after routine cataract surgery. METHODS A prospective, randomized, double-blind placebo-controlled trial of 69 hospital patients undergoing cataract surgery. Celecoxib 200 mg twice daily or placebo was given immediately after(More)