Lata Venkataraman

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OBJECTIVES To evaluate microbiological properties of methicillin-resistant Staphylococcus aureus (MRSA) during prolonged vancomycin therapy. METHODS We evaluated vancomycin susceptibility and heteroresistance, accessory gene regulator (agr) function, autolysis, biofilm production and in vitro vancomycin killing in serial MRSA bloodstream isolates obtained(More)
BACKGROUND Methicillin-resistant Staphylococcus aureus (MRSA) infections diagnosed at hospital admission are often referred to as community-acquired. This designation may include MRSA strains previously acquired in a healthcare setting (healthcare-associated) as well as those that have emerged from community-based S. aureus strains. METHODS To understand(More)
OBJECTIVES The G2576T mutation in domain V of 23S rRNA has been most often associated with the rare cases of linezolid resistance in Staphylococcus aureus. In a linezolid-susceptible S. aureus (A8761B) possessing a single mutated (G2576T) copy, originally derived from a resistant clinical isolate, we assessed the persistence of the mutation on further(More)
  • Spiramycin Clarithromycin, Azithromycin Clindamycin, +497 authors Kazuhiro Yamada
  • 2012
Comments • legend: red: drug resistant; green: drug susceptible; yellow: intermediate drug resistant; gray: contrary information of no CLSI interpretation; white: not information is found, • drug susceptibility information for the strain TW20 was confirmed by e-mail correspondence with the authors of [16] • drug susceptibility information for the strain(More)
conducted a retrospective study of the clinical aspects of bacteremia caused by methicillin-resistant Staphylococcus aureus (MRSA) with heterogeneously reduced susceptibility to vancomycin. Bloodstream MRSA isolates were screened for reduced susceptibility by using brain-heart infusion agar, including 4 mg/L vancomycin with and without 4% NaCl. Patients(More)
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