Lasse Linnerup Christiansen

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Neuroscience has fundamentally changed the understanding of learning and memory within recent years. Here, the authors discuss a number of specific areas where they believe new understanding of the CNS from basic science is having a fundamental impact on neurorehabilitation and is leading to new therapeutic approaches. These areas have constituted a basis(More)
OBJECTIVE To determine if acetabular dysplasia increases the risk of incident hip osteoarthritis (OA) among elderly white women. METHODS Baseline and followup anteroposterior pelvic radiographs were obtained a mean of 8 years apart, and read for individual radiographic features (IRFs) of hip OA; summary grades (0-4) were then assigned based on the IRFs(More)
It is well established that unilateral motor practice can lead to increased performance in the opposite non-trained hand. Here, we test the hypothesis that progressively increasing task difficulty during long-term skill training with the dominant right hand increase performance and corticomotor excitability of the left non-trained hand. Subjects practiced a(More)
Fifty-two children aged 6-46 months (mean 19 months), hospitalized for acute gastroenteritis (GE), were randomized after oral rehydration to receive 7 days of either traditional gradual refeeding (GR) or rapid refeeding (RR), the latter consisting of a full-strength lactose-limited diet, including lactase-treated whole milk. The study focused on the effect(More)
A single bout of high intensity aerobic exercise (~90% VO2peak) was previously demonstrated to amplify off-line gains in skill level during the consolidation phase of procedural memory. High intensity exercise is not always a viable option for many patient groups or in a rehabilitation setting where low to moderate intensities may be more suitable. The aim(More)
High intensity aerobic exercise amplifies offline gains in procedural memory acquired during motor practice. This effect seems to be evident when exercise is placed immediately after acquisition, during the first stages of memory consolidation, but the importance of temporal proximity of the exercise bout used to stimulate improvements in procedural memory(More)
Increasingly, streaming positions from moving objects in blended indoor/outdoor spaces are used to deliver new types of real-time location-based services. To support such scenarios, this paper presents the Searchlight Graph (SLG) model and the associated Searchlight Continuous Query Processing Framework (CQPF) for (predictive) Continuous Query Processing(More)
Monitoring the actual and predicted flow of receptor-based (e.g. RFID) moving objects can be useful in a variety of applications, e.g., to predict congestion in an airport bag handling system or reason about the location of a lost bag. In this paper, we propose the Flow Representation Graph (FRG) model, which, unlike earlier work, captures both the actual(More)
In this paper we demonstrate FlowPredictor, a novel Continuous Query Processing Framework (CQPF) for continuous query processing of the actual and predicted flow of receptor-based moving objects in a symbolic space covering both indoor and outdoor space. FlowPredictor enables spatiotemporal selection, aggregate, nested, and complex queries to be evaluated(More)
Human and animal studies have documented that neural circuitries in the spinal cord show adaptive changes caused by altered supraspinal and/or afferent input to the spinal circuitry in relation to learning, immobilization, injury and neurorehabilitation. Reversible adaptations following, e.g. the acquisition or refinement of a motor skill rely heavily on(More)