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BACKGROUND Levosimendan, a novel calcium sensitiser, improves myocardial contractility without causing an increase in myocardial oxygen demand. We compared the effects of levosimendan and dobutamine on haemodynamic performance and clinical outcome in patients with low-output heart failure. METHODS Patients were recruited into a multicentre, randomised,(More)
—This paper analyses the effects of Network-on-Chip (NoC) models written in SystemC on simulation speed. Two Register Transfer Level (RTL) models and Approximately Timed (AT) and Loosely Timed (LT) Transaction Level (TL) models are compared against reference RTL VHDL 2D mesh model. Three different mesh sizes are evaluated using a commercial simulator and(More)
— This paper presents a set of 9 application traffic models for benchmarking Networks-on-Chip designs. Common benchmarks allow fair comparison, reproduction of research results, and accelerate NoC development. The set is based on real applications found in literature and executable on freely available benchmarking tool called Transaction Generator (TG). It(More)
BACKGROUND The short-term infusion of levosimendan (Levo) improves hemodynamic function in patients with decompensated heart failure. The metabolites of Levo have a prolonged half-life, and one is hemodynamically active. The goal of this study was to determine whether the hemodynamic effects of Levo are sustained during a long-term infusion and beyond the(More)
This paper presents a software-based implementation for the MIMO transmitter baseband processing conforming to the IEEE802.11ac standard on a DSP core with vector extensions. The transmitter is implemented in four different transmission scenarios, which include 2×2 and 4×4 MIMO configurations, yielding beyond 1Gbps transmit bit rate. The(More)
IP-XACT, the recent IEEE1685 standard, defines metadata format for IP packing and integration in System-on-Chip designs. It was originally proposed for hardware descriptions, but we have extended it for software, HW/SW mappings and application communication abstraction. The latter is realized with Multicore Association MCAPI that is a lightweight message(More)
BACKGROUND The rapid expansion in the use of electronic health records (EHR) has increased the number of medical errors originating in health information systems (HIS). The sociotechnical approach helps in understanding risks in the development, implementation, and use of EHR and health information technology (HIT) while accounting for complex interactions(More)
It is not clear whether high doses of inhaled steroids have a greater sparing effect than low doses on the requirement for systemic steroids. In a randomised, double-blind, multicentre study, we compared the effects of high-dose (1500 micrograms/day) and low-dose (300 micrograms/day) inhaled beclomethasone dipropionate (BDP) in patients with severe asthma(More)
Sound and timely scientific advice is an essential requirement for the Commission to pursue modern, responsive and sustainable health systems. To this end, the Commission has set up a multidisciplinary and independent Expert Panel which provides advice on effective ways of investing in health (Commission Decision 2012/C 198/06). The core element of the(More)
In this paper, a software-based implementation for the Multiple Input and Multiple Output (MIMO) receiver baseband processing conforming to the IEEE 802.11ac standard on a DSP core with vector extensions is presented. The implementation is carried out for different operation points including 2×2 and 4×4 MIMO configurations, yielding beyond(More)