Laskeesha Carmichael

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We have studied serum immunoreactive erythropoietin (SIE) levels in 28 patients with sickle cell anemia (SCA) without renal insufficiency and in 17 patients with nonhemoglobinopathy anemias of comparable severity using a sensitive radioimmunoassay procedure. An exponential relationship between SIE level and degree of anemia was noted in all patients.(More)
Immunotherapeutic response in cancer patients, specifically those attributed to antibody-dependent cellular cytotoxicity (ADCC), may be variable dependent upon an individual’s genotype. A recent Eastern Cooperative Oncology Group (ECOG) Phase III clinical trial, E4402, sought to optimize therapeutic administration of single agent rituximab (RTX) in patients(More)
In an attempt to uncover potential genetic sources of the clinical diversity of sickle cell anemia, we have characterized homozygous SS patients in the following ways: percentage of dense red blood cells (% F4) as determined from Percoll-Stractan continuous density gradients, alpha gene deletion, average percentage of hemoglobin F (% HbF), hemoglobin in(More)
The presence of more than one form of immunoreactive erythropoietin was suggested by discrepancies between the levels of immunologically detectable and biologically active erythropoietin in the sera of normal individuals and patients with end-stage renal disease. In both groups, the level of immunologically detectable hormone was significantly higher than(More)
Associations of Fc gamma receptor (FcgR2a, FcgR3a and FcgR2c) genotype with outcome in metastatic renal cell carcinoma (mRCC) patients receiving high dose interleukin 2 (HD-IL2) Amy K Erbe, Wei Wang, Kyung Mann Kim, Laskeesha Carmichael, MIkayla Gallendberger, Dustin Hess, Eneida A Mendonca, Yiqiang Song, Jacquelyn A Hank, Su-Chun Chen, Sabina Signoretti,(More)
We performed a prospective study to examine the epidemiology and microbiology of peritonitis complicating acute intermittent peritoneal dialysis (IPD) performed in an in-hospital setting for the management of acute and chronic renal failure and to see the effect of a closed-drainage system on altering the frequency and cause of peritonitis. Over a 15-month(More)
e13556 Background: We have shown that nearly all patients with solid tumors have an increase in tumor proliferation during acute withdrawal of SU as quantified by FLT PET/CT imaging. We hypothesize that this results from compensatory increases in proangiogenic factors such as VEGF and HIF1-α during SU exposure. We conducted this study to understand the(More)