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  • Natalia A. Liapounova, Vladimír Hampl, Paul M. K. Gordon, Christoph W. Sensen, Lashitew Gedamu, Joel B Dacks
  • Biology, Medicine
  • Eukaryotic cell
  • 2006 (First Published: 1 December 2006)
  • All eukaryotes carry out glycolysis, interestingly, not all using the same enzymes. Anaerobic eukaryotes face the challenge of fewer molecules of ATP extracted per molecule of glucose due to theirContinue Reading
  • Vasanthakrishna Mundodi, Ashwini S. Kucknoor, Lashitew Gedamu
  • Biology, Medicine
  • BMC Molecular Biology
  • 2004 (First Published: 3 February 2005)
  • BackgroundThe parasitic protozoa belonging to Leishmania (L.) donovani complex possess abundant, developmentally regulated cathepsin L-like cysteine proteases. Previously, we have reported theContinue Reading
  • Nada S Daifalla, Abebe Genetu Bayih, Lashitew Gedamu
  • Biology, Medicine
  • Experimental parasitology
  • 2011 (First Published: 1 November 2011)
  • In this study, we assessed the immune response of two Leishmania donovani recombinant proteins: iron superoxide dismutase B1 (SODB1) and peroxidoxin 4 (Pxn4) in BALB/c mice. Assessment of theContinue Reading
  • Amol Bhargava, James A Cotton, +4 authors Matthew S Bogyo
  • Biology, Medicine
  • PloS one
  • 2015 (First Published: 3 September 2015)
  • Giardia duodenalis infections are among the most common causes of waterborne diarrhoeal disease worldwide. At the height of infection, G. duodenalis trophozoites induce multiple pathophysiologicalContinue Reading
  • Nada S Daifalla, Abebe Genetu Bayih, Lashitew Gedamu
  • Biology, Medicine
  • Experimental parasitology
  • 2012 (First Published: 1 July 2012)
  • In this study, we tested the protective efficacy of recombinant Leishmania donovani iron superoxide dismutase B1 (SODB1) against Leishmania major infection in BALB/c mice. Mice were challenged withContinue Reading
  • Abebe Genetu Bayih, Nada S Daifalla, Lashitew Gedamu
  • Biology, Medicine
  • PLoS neglected tropical diseases
  • 2014 (First Published: 11 December 2014)
  • BACKGROUND To date, no universally effective and safe vaccine has been developed for general human use. Leishmania donovani Peroxidoxin-1 (LdPxn-1) is a member of the antioxidant family of proteinsContinue Reading