Lars Werner

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BACKGROUND AND PURPOSE AT1 receptor blockers (ARBs) represent an approach for treating metabolic syndrome due to their potency in reducing hypertension, body weight and onset of type 2 diabetes. The mechanism underlying ARB-induced weight loss is still unclear. EXPERIMENTAL APPROACH Leptin resistance tests (LRTs) in diet-induced obese or lean rats were(More)
Hypothalamic functions, including feeding behavior, show a high degree of plasticity throughout life. Doublecortin (DCX) is a marker of plasticity and neuronal migration expressed in the hypothalamus. Therefore, we wanted to map the fate of DCX(+) cells in the arcuate nucleus (ARC) of the hypothalamus. For this purpose, we generated a BAC transgenic mouse(More)
Whenever digital libraries or knowledge management systems are to be automatically filled with web pages from the internet, document classification of the web pages is one of the major challenges. We present an approach which uses HTML tags in order to improve the quality of the hypertext document classification. Our approach uses weighting of HTML tags for(More)
Functional proteomics aims to describe cellular protein networks in depth based on the quantification of molecular interactions. In order to study the interaction of adenosine-3',5'-cyclic monophosphate (cAMP), a general second messenger involved in several intracellular signalling networks, with one of its respective target proteins, the regulatory (R)(More)
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