Lars Laurell

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BACKGROUND The objective of this study was to assess the adjunctive clinical effect of the administration of systemic amoxicillin and metronidazole in the non-surgical treatment of generalized aggressive periodontitis (GAP). METHODS Forty-one systemically healthy subjects with GAP were included in this 6-month double-blind, placebo-controlled, randomized(More)
BACKGROUND It is important that peri-implant bone breakdown caused by, for example, undue load and/or peri-implantitis, is prevented or minimized. Some continuous loss of marginal bone is generally accepted, but the question remains as to what extent it must occur. PURPOSE The purpose of this study was to compile and compare data on peri-implant marginal(More)
INTRODUCTION The baseline radiographic defect angle has previously been correlated with the clinical outcomes of intrabony defects treated with access flap or guided tissue regeneration. The aim of this study was to investigate whether an association exists between baseline radiographic defect angle and treatment outcome when enamel matrix derivative (EMD)(More)
OBJECTIVE To compare the short-term performance of subgingival local delivery of 2% minocycline gel and conventional subgingival debridement in supportive periodontal therapy (SPT) patients. METHODS Forty adult patients having completed active treatment for moderate to advanced chronic periodontitis were included in a randomized, controlled, single masked(More)
The aim of this study was to present data from clinical and radiographic examinations on oral health in two cross-sectional studies carried out in 1973 and 1983. A random sample of approximately 1000 individuals, evenly distributed in the age groups 3, 5, 10, 15, 20, 30, 40, 50, 60 and 70 years was studied for each of these two years. In the 1983-year(More)
This article reviews studies presented during the last 20 years on the surgical treatment of intrabony defects. Treatments include open flap debridement alone (OFD); OFD plus demineralized freeze-dried bone allograft (DFDBA), freeze-dried bone allografts (FDBA), or autogenous bone; and guided tissue regeneration (GTR). The review includes only studies that(More)
BACKGROUND Freeze-dried acellular dermal matrix (ADM) allograft, originally used for full-thickness burn wounds, was recently introduced as an alternative to the autogenous free gingival graft (FGG) in achieving increased attached keratinized tissue. The aim of part 1 of this study was to investigate the clinical efficacy of the ADM allograft for this(More)
The objectives of the present investigation were to analyze intraoral radiographs and to study 1) the distribution of the distance between the cemento-enamel junction (CEJ) and the alveolar bone level (BL) and 2) the prevalence and severity of vertical defects, and furcation lesions in 416 individuals seeking dental care. Full mouth radiographs were(More)
BACKGROUND Radiographic measurements are often used as a substitute for direct clinical measurements requiring re-entry surgery for follow-up outcome studies. AIMS (1) To assess the reliability of clinical and radiographic measurements of periodontal defects as compared to direct bone measurements during surgical procedures, and (2) to assess the(More)