Lars Eriksson

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OBJECTIVE The ECAT EXACT HR is a newly designed CTI-Siemens PET scanner with high spatial resolution. Its physical performance with respect to resolution, count rate efficiency, and scatter was investigated and evaluated with phantom studies. MATERIALS AND METHODS The new tomograph consists of three rings of 112 BGO block detectors (50 mm x 23 mm x 30 mm(More)
[11C]Raclopride binding to central D2-dopamine receptors in humans has previously been examined by positron emission tomography (PET). Based on the rapid occurrence of binding equilibrium, a saturation analysis has been developed for the determination of receptor density (Bmax) and affinity (Kd). For analysis of PET measurements obtained with other ligands,(More)
An adjustable computerized atlas of the human brain has been developed, which can be adapted to fit individual anatomy. It is primarily intended for positron emission tomography (PET) but may also be used for single photon emission CT, transmission CT, magnetic resonance imaging, and neuroimaging-based procedures, such as stereotactic surgery and(More)
Previous studies have shown that sensory stimulation and voluntary motor activity increase regional cerebral glucose consumption and regional cerebral blood flow (rCBF). The present study had 3 purposes: (1) to examine whether pure mental activity changed the oxidative metabolism of the brain and, if so, (2) to examine which anatomical structures were(More)
The Cologne Special is a prototype of the ECAT EXACT (model 921), a new generation of Siemens-CTI PET scanners. It consists of three rings of 48 BGO block detectors each, covering an axial field of view of 16.2 cm with a patient port of 56.2 cm diameter. This results in a total of 24 rings with 384 crystals each, giving 47 contiguous image planes in(More)
BACKGROUND Interstitial cells of Cajal (ICCs) express the tyrosine kinase receptor c-kit, which is required for their development and spontaneous pacemaker activity in the bowel. From murine models it has been proposed that ICCs do not develop until after birth, but more recent findings indicate that c-kit is expressed early in the embryonic period. The(More)
The PC2048-15B is the brain version of the new generation of Scanditronix positron camera systems. It is based on a detection unit with 16 scintillating crystals mounted on 2 dual photomultiplier tubes. A system description is given and preliminary test results including spatial resolution, sensitivity to true and random coincidences, scatter correction,(More)
We investigated with PET the cerebral activation pattern elicited by the perceptual maze test (PMT), a neuropsychological test used to evaluate organic brain injury. The PMT examines visuospatial skill, general intelligence, visually guided motor planning, and the ability to obey rules. Eight right-handed volunteers were examined with PET using the tracer(More)
Turbo charged SI engines are a major possibility in the current trend of down-sized engines with preserved drivability performance. Considering control and supervision it is favorable to have a mean value model to be used e.g. in observer design. Such models of turbo engines are similar to those of naturally aspirated engines, but there are some special(More)
A mean-value model of a diesel engine with a variable-geometry turbocharger (VGT) and exhaust gas recirculation (EGR) is developed, parameterized, and validated. The intended model applications are system analysis, simulation, and development of modelbased control systems. The goal is to construct a model that describes the gas flow dynamics including the(More)