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Borrelia burgdorferi, the Lyme disease spirochete, has a genome comprised of a linear chromosome and up to 21 plasmids. Loss of plasmids is associated with decreased infectivity and pathogenicity. Sixteen transformants were generated by transforming the noninfectious clone 5A13 with the recombinant plasmid pBBE22. The transformants were classified into nine(More)
BACKGROUND Fetal stress has been linked to adult atherosclerosis, obesity, and diabetes. Epidemiology studies have associated fetal exposure to maternal smoking and postnatal exposure to environmental tobacco smoke (ETS) with increased asthma risk. OBJECTIVE We tested the hypothesis, in a mouse model of asthma, that in utero ETS exposure alters airway(More)
ii ACKNOWLEDGEMENTS I would like to express my great appreciation for my major professor Dr. James E. Miller for giving me the opportunity to learn and pursue this degree under his mentorship. I cannot thank him enough for all that he taught me in the field of veterinary parasitology as well as research in general. Also, my thanks go to my other committee(More)
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