Larry L. Green

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  • C H Bischof, L L Green, K J Haigler, T L Knauff, Panama City, Florida
  • 1994
Sensitivity derivative (SD) calculation via automatic differentiation (AD) typical of that required for the aerodynamic design of a transport-type aircraft is considered. Two ways of computing SD via code generated by the ADIFOR automatic differentiation tool are compared for efficiency and applicability to problems involving large numbers of design(More)
MCAM/MUC18 expression correlates with tumor thickness and metastatic potential of human melanoma cells in nude mice. Moreover, ectopic expression of MUC18 in primary cutaneous melanoma cells leads to increased tumor growth and metastasis in vivo. Here we tested the effect of a fully human anti-MUC18 antibody, ABX-MA1, on angiogenesis, tumor growth, and(More)
Notice: This document has been prepared to assist IEEE 802.11. It is offered as a basis for discussion and is not binding on the contributing individual(s) or organization(s). The material in this document is subject to change in form and content after further study. The contributor(s) reserve(s) the right to add, amend or withdraw material contained(More)
  • A Jakobovits, A L Moore, L L Green, G J Vergara, C E Maynard-Currie, H A Austin +1 other
  • 1993
Introduction of DNA fragments, hundreds of kilobases in size, into mouse embryonic stem (ES) cells would greatly advance the ability to manipulate the mouse genome. Mice generated from such modified cells would permit investigation of the function and expression of very large or crudely mapped genes. Large DNA molecules cloned into yeast artificial(More)
  • Sharon L Padula, Natalia Alexandrov, Lawrence L Green, S L Padula, N Alexandrov, L L Green
  • 1996
The NASA Langley Research Center supports a wide variety of multidisciplinary design optimization (MDO) research and requires a set of standard MDO test problems for evaluating and comparing the products of this research. This paper proposes a WorldWide Web based test suite for collecting, distributing, and maintaining the standard test problems. A(More)
An objective of the High Performance Computing and Communication Program at the NASA Langley Research Center is to demonstrate multidisciplinary shape and sizing optimization of a complete aerospace vehicle configuration by using high-fidelity finite-element structural analysis and computational fluid dynamics aerodynamic analysis in a distributed,(More)
The relationship between variable (V) gene complexity and the efficiency of B cell development was studied in strains of mice deficient in mouse antibody production and engineered with yeast artificial chromosomes (YACs) containing different sized fragments of the human heavy (H) chain and kappa light (L) chain loci. Each of the two H and the two kappa(More)
Substance abuse has had a devastating impact on the lives of millions. As substance use and abuse continues to ravage communities, researchers remain in the dark about what works to ensure successful recovery from addiction. In searching for the answers, researchers have often overlooked the role of religious and spiritual practices and beliefs in(More)
  • N M Alexandrov, R M Lewis, C R Gumbert, L L Green, P A Newman
  • 2000
This work discusses an approach, the Approximation Management Framework (AMF), for solving optimization problems that involve computationally expensive simulations. AMF aims to maximize the use of lower-fidelity, cheaper models in iterative procedures with occasional , but systematic, recourse to higher-fidelity, more expensive models for monitoring the(More)
  • N M Alexandrov, R M Lewis, C R Gumbert, L L Green, P A Newman
  • 1999
This work discusses an approach, the Approximation Management Framework (AMF), for solving optimization problems that involve computationally expensive simulations. AMF aims to maximize the use of lower-fidelity, cheaper models in iterative procedures with occasional , but systematic, recourse to higher-fidelity, more expensive models for monitoring the(More)