Learn More
A new system for grading age-related maculopathy is described and measures of reliability are reported. A number of characteristics of age-related maculopathy are graded in a semiquantitative fashion from stereoscopic 30 degrees color fundus photographs, using a grid to define subfields, standard circles printed on plastic to assess size and area, and a(More)
PURPOSE To describe the cross-sectional relationship between retinal arteriolar and venular diameters with age and blood pressure. METHODS A population-based study was conducted in Beaver Dam, Wisconsin (n=4926, age range, 43-84 years). Retinal photographs of right eyes taken at the baseline examination (1988-90) were digitized. All arterioles and venules(More)
PURPOSE To describe the cross-sectional relationships between age, blood pressure (BP), and quantitative measures of retinal vessel diameters in an older Australian population. METHODS Retinal photographs from right eyes of participants (n = 3654, aged 49+ years) in the Blue Mountains Eye study taken during baseline examinations (1992-1994) were(More)
BACKGROUND Retinal microvascular abnormalities reflect damage from hypertension and other vascular processes. We examined the relation of such abnormalities to incident stroke. METHODS A cohort of 10358 men and women (aged 51 to 72 years) living in four US communities underwent retinal photography and standard grading for retinal microvascular(More)
PURPOSE To examine the cross-sectional relationship of the metabolic syndrome (hypertension, hyperglycemia, central obesity, and dyslipidemia) and retinal microvascular abnormalities in middle-aged men and women. METHODS A population-based, cross-sectional study involving 11,265 persons aged 49 to 73 years who had retinal photography from 1993 through(More)
PURPOSE It remains unclear whether reduced retinal blood flow and smaller arterioles, reported to exist in patients with open-angle glaucoma (OAG), are a cause or a consequence of ganglion cell loss. We examined whether baseline retinal vessel diameters were related to incident (i)OAG or incident optic disc changes in a population-based sample. METHODS In(More)
This study assessed the correlation between computer-assisted retinal vessel measurements of right and left eyes, from subjects in a defined, community-based older population. Retinal photographs from participants in the Blue Mountains Eye Study were digitized. All retinal arterioles and venules located 0.5-1.0 disc diameters from the optic disc margin were(More)
A robust and automatic system has been developed to detect the visual axis and extract important feature landmarks from slit-lamp photographs, and objectively grade the severity of nuclear sclerosis based on the intensities of those landmarks. Using linear regression, we first select the features that play important roles in classification, and then fit a(More)
Stereoscopic fundus photography of seven fields has become standard procedure for detecting diabetic retinopathy. However, the question has arisen as to whether adequate detection of retinopathy can be achieved with fewer fields. This question was investigated in a population-based study of 2694 diabetic persons. Retinopathy levels derived from the detailed(More)
OBJECTIVE To examine retinal vascular caliber, an indicator of early microvascular disease and depression in patients with Type 2 diabetes. METHODS We conducted a clinic-based study, comparing participants with Type 2 diabetes with major depression (n = 43), without depression (n = 49), and healthy controls without diabetes or depression (n = 54). Retinal(More)