Lara Mendes de Almeida

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Staphylococcus aureus is one of the most important infectious mastitis causative agents in small ruminants. In order to know the distribution of Staph. aureus strains associated with infectious mastitis in flocks of sheep in the northeast of Brazil and establish whether these clones are related to the strains distributed internationally, this study analysed(More)
Since Staphylococcus aureus can cause several types of diseases, the development of antibiotic resistance poses an even greater threat to public health. S. aureus is known to possess the adaptive capability to promptly respond to antibiotics, making it resistant and increasingly difficult to treat; methicillin-resistant strains of S. aureus are a major(More)
Linezolid, the first oxazolidinone class agent to be introduced clinically, has broad activity against many important multidrug-resistant Gram-positive pathogens, including methicillinresistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). Linezolid inhibits protein synthesis by interacting with 23S rRNA in the 50S ribosomal(More)
We report the whole-genome sequence (WGS) of an in vitro susceptible derivative revertant mutant from a bloodstream isolate involved in a nosocomial outbreak in Brazil. The WGS comprises 2.5 Mb with 2,500 protein-coding sequences, 16rRNA genes, and 60 tRNA genes.
Lara M. de Almeida, Maria Rita E. de Araújo, Marta F. Iwasaki, Andrey G. Sacramento, Darlan Rocha, Leila P. da Silva, Mónica Pavez, Artemir C. de Brito, Laís Carolina S. Ito, Ana C. Gales, Nilton Lincopan, Jorge L. M. Sampaio, Elsa M. Mamizuka Department of Clinical Analysis, School of Pharmacy, University of São Paulo, São Paulo, Brazil; Laboratory of(More)
Intrinsic mechanisms leading to carbapenem-induced membrane impermeability and multidrug resistance are poorly understood in clinical isolates of Enterobacteriaceae. In this study, molecular behaviours during the establishment of membrane impermeability in members of the Enterobacteriaceae family under imipenem selective pressure were investigated. Clinical(More)