Lara-Jill Jennings

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Destruction of collagen within osteoarthritic cartilage depends in part on collagen-degrading matrix metalloproteases (MMP). Degradative fragments of type II collagen (Col II) occur in normal and in osteoarthritic cartilage, and may contribute to regulation of matrix turnover by interfering with normal cell-matrix communication pathways. Therefore, the(More)
Cartilage matrix degradation generates collagen type II fragments. The objective of this study is to explore the possibility that these collagen fragments may be part of an endogenous metabolic feedback. Initially, collagen fragments were extracted from normal or osteoarthritic cartilage, as part of a matrix fragment preparation. Later, collagen fragments(More)
The purpose of this study was to develop, digitally record, evaluate, and psychometrically equate a set of Mandarin bisyllabic word lists for use in measurement of speech discrimination. Familiar bisyllabic words were digitally recorded by male and female talkers of Standard Mandarin. Percentage of correct word recognition was measured for each word at ten(More)
The aim of this investigation was to develop, digitally record, evaluate, and equate Mandarin trisyllabic words, which could then be used to measure the SRT. A selection of 90 frequently utilized trisyllabic words were digitally recorded by male and female talkers of Standard Mandarin and presented to 20 normally hearing subjects at 13 intensity levels (-10(More)
Attempts to produce in animals lung lesions mediated by anti-alveolar basement membrane (ABM) antibodies have thus far been inconclusive. The aim of the present study was to test the hypothesis that increased permeability of the endothelial cell lining is needed before circulating antibodies can gain access and bind to ABM. A goat antiserum was prepared(More)
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