Lanying Zhang

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OBJECTIVE Candidate gene association studies and genome-wide association studies (GWAs) have identified a large number of single nucleotide polymorphisms (SNPs) loci affecting susceptibility to rheumatoid arthritis (RA). However, for the same locus, some studies have yielded inconsistent results. To assess all the available evidence for association, we(More)
Traditional permutation (TradPerm) tests are usually considered the gold standard for multiple testing corrections. However, they can be difficult to complete for the meta-analyses of genetic association studies based on multiple single nucleotide polymorphism loci as they depend on individual-level genotype and phenotype data to perform random shuffles,(More)
According to the general planning requirements of Outside Management Center (OMC for short) of Hongqiao Airport and on the basis of water management business description, this paper divides three levels for the water information system management structure, designs the overall structure of the water information system, analyses the function of the system(More)
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