Learn More
OBJECTIVE To quantify relationships between dietary intake of zinc and antioxidant nutrients and early and late age-related maculopathy (ARM). DESIGN A retrospective longitudinal cohort design using data pertaining to diets in the past (1978-1980), which were assessed retrospectively using a food frequency questionnaire. SETTING Beaver Dam, Wis. (More)
Relations between diet and nuclear opacities in the lens of the eye were investigated in a population-based cohort of middle-aged and older adults who lived in Beaver Dam, Wisconsin. Nuclear sclerosis was assessed from photographs of the lens taken during 1988-1990 in 1,919 persons in the Beaver Dam Eye Study. Diets in the past (1978-1980) were assessed(More)
PURPOSE The authors evaluated the cross-sectional and longitudinal relations between lens opacities and intake of vitamins and minerals in supplements. METHODS Type and quantity of vitamins and minerals taken currently and 10 years before interview were obtained in a population-based sample of persons in the Nutritional Factors in Eye Disease Study (n =(More)
A likelihood based method is proposed for multivariate categorical data. It is assumed that, together with the marginal outcomes, the set of pairwise associations between outcomes is of scientific interest. The focus is on binary outcomes and it is indicated how the proposed method generalizes to categorical outcomes. A connection with second-order(More)
We evaluated the reproducibility of a modified version of the National Cancer Institute diet history questionnaire and also studied comparability of nutrient estimates from this questionnaire to those from four 2-d food records. Subjects (n = 211) were from a population-based sample of middle-aged and older adults participating in the Beaver Dam Eye Study(More)
PURPOSE To evaluate a possible association of glaucoma with alcohol ingestion and cigarette-smoking behavior. METHODS A population-based survey was performed of persons 43 to 84 years of age in Beaver Dam, Wisconsin (n = 4926). The diagnosis of glaucoma was based on visual field testing, measurement of intraocular pressure, and cup-to-disc ratios based on(More)
PURPOSE Because there are few epidemiologic data examining the relationship between alcohol use and age-related maculopathy, we investigated this relationship via the population-based Beaver Dam Eye Study. METHODS Alcohol consumption in the year before examination was determined by a standardized questionnaire. Age-related maculopathy status was(More)
Intake of macronutrients and micronutrients was estimated from a diet history questionnaire in a population-based sample of persons (n = 2152), 43-86 y of age. Men and women 65 y of age or older consumed less protein, fat, cholesterol, niacin, riboflavin, calcium, iron, zinc and lycopene than their middle-aged counterparts. After including nutrient intake(More)
PURPOSE To investigate the relationship between microalbuminuria and the presence and severity of diabetic retinopathy in a large population-based cohort of individuals with diabetes. METHODS Microalbuminuria was measured by an agglutination inhibition assay in random urine samples obtained from participants in the Wisconsin Epidemiologic Study of(More)