Lane C McConnell

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We computationally investigate the dynamics of a vesicle exposed to uniform DC or AC electric fields. We employ the two-dimensional boundary integral method in order to simulate vesicle deformation under experimental conditions where peculiar drum-like ("squared") shapes have been observed. The vesicle membrane is modeled as an infinitely thin, capacitive,(More)
We computationally investigate the deformation of a closed bilayer membrane (vesicle) in a DC electric pulse with a goal of understanding cell electroporation. The electric stresses exerted on the area-incompressible interface generate non-uniform tension that can exceed the membrane lysis tension and drive pore opening. Using the two-dimensional boundary(More)
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