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  • Lance M. Villeneuve, Leann M Tiede, Brenda M. Morsey, Howard S. Fox
  • Biology, Medicine
  • Journal of proteome research
  • 2013 (First Published: 4 October 2013)
  • Mitochondria are implicated in a variety of degenerative disorders and aging. Mitochondria are responsive to the oxygen in their environment, yet tissue culture is performed at atmospheric (21%)Continue Reading
  • Kelly L. Stauch, Lance M. Villeneuve, Phillip R Purnell, Brendan M. Ottemann, Katy Emanuel, Howard S. Fox
  • Biology, Medicine
  • Proteomics. Clinical applications
  • 2016 (First Published: 1 December 2016)
  • PURPOSE Mutations in PTEN-induced putative kinase 1 (Pink1), a mitochondrial serine/threonine kinase, cause a recessive inherited form of Parkinson's disease (PD). Pink1 deletion in rats results in aContinue Reading
  • Kelly L. Stauch, Lance M. Villeneuve, Phillip R Purnell, Sanjit Pandey, Chittibabu Guda, Howard S. Fox
  • Biology, Medicine
  • Data in brief
  • 2016 (First Published: 1 December 2016)
  • This article reports changes in the striatal non-synaptic mitochondrial proteome of DJ-1, Parkin, and PINK1 knockout (KO) rats at 3 months of age. DJ-1, Parkin, and PINK1 mutations causeContinue Reading
  • Lance M. Villeneuve, Kelly L. Stauch, Howard S. Fox
  • Biology, Medicine
  • Journal of proteomics
  • 2014 (First Published: 1 September 2014)
  • UNLABELLED Many biological processes converge on the mitochondria. In such systems, where many pathways converge, manipulation of the components can produce varied and far-reaching effects. Due toContinue Reading
  • Lance M. Villeneuve, Phillip R Purnell, Kelly L. Stauch, Shannon E Callen, Shilpa Buch, Howard S. Fox
  • Biology, Medicine
  • Journal of NeuroVirology
  • 2016 (First Published: 1 October 2016)
  • With the advent of the combination antiretroviral therapy era (cART), the development of AIDS has been largely limited in the USA. Unfortunately, despite the development of efficacious treatments,Continue Reading