Lance M. Moses

Learn More
Rett syndrome is a neurodevelopmental disorder of early postnatal brain growth in girls. Patients show a normal neonatal period with subsequent developmental regression and a loss of acquired skills (communication and motor skills), deceleration of head growth, and development of typical hand stereotypies. Recent studies have shown that mutations in the(More)
A series of 2-phenyl-3H-imidazo[4,5-b]pyridine-3-acetamides were designed and synthesized as non-benzodiazepine anxiolytics based on a molecular disconnection of a typical 1,4-benzodiazepine (BZD). A number of these compounds showed submicromolar potency in a [3H]benzodiazepine binding assay in vitro and good potency in protecting rodents against(More)
Of 74,920 babies live born in Oxford between 1985 and 1996, 41 (0.5 per 1000 95% CI 0.4-0.7) developed definite, culture confirmed, early onset (< 48 hours) group B streptococcal infection and 32 (0.4 per 1000 95% CI 0.3-0.6) developed probable infection (sepsis plus colonisation). There was no significant variation in incidence with time. The mortality(More)
Quantum dot solar cells seek to surpass the solar energy conversion efficiencies achieved by bulk semiconductors. This new field requires a broad selection of materials to achieve its full potential. The 12 nm spherical protein ferritin can be used as a template for uniform and controlled nanocrystal growth, and to then house the nanocrystals for use in(More)
Iron-containing ferritin has been used for light harvesting and as a photocatalyst. In this study, we test the hypothesis that changing the ironmineral core composition can alter the light harvesting and photocatalytic properties of ferritin, by co-depositing iron in the presence of halides or oxo-anions. This caused the anions to be incorporated into the(More)
  • 1