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Cinnamaldehyde is a principle compound isolated from Guizhi-Tang, which is a famous traditional Chinese medical formula used to treat influenza, common cold and other pyretic conditions. The aim of the present study was to investigate the effects of cinnamaldehyde on expression and activity of cyclooxygenase (COX) and prostaglandin E(2) (PGE(2)) in rat(More)
OBJECTIVE To explore the molecular mechanisms of propofol in myocardial protection, the activation of nuclear factor-kappaB (NF-kappaB) and the apoptosis of cardiomyocytes were examined. METHODS Rat myocardium I/R injury was induced by occluding the left main coronary artery for 30 min and reperfusion for 2 h. Propofol was intravenously given 15 min(More)
Fever, an elevation in body temperature, is thought to be terminally mediated by prostaglandin E(2) (PGE(2)). Both Guizhi Tang (GZT) and its active fraction A (Fr.A) showed an antipyretic effect in rats. 3-Phenyl-2-propene-1-ol was one of the active compounds isolated from Fr.A. In the present study, we examined the influence of interleukin-1beta (IL-1beta)(More)
Combined with the development of computer digital control technology and intelligent control theory, an advanced intelligent fuzzy control method with self-study ability used in SVC (static VAr compensator), was put forward in the paper. The control system can acquire and adjust control rules automatically according to the controlled object. Therefore, the(More)
ETHNOPHARMACOLOGICAL RELEVANCE Scutellaria baicalensis Georgi (Lamiaceae) is often included as an ingredient in traditional Chinese compound prescriptions for the treatment of fever-related or inflammatory conditions. AIM OF THE STUDY The present work was to further uncover the analgesic mechanisms of baicalin (a known principal constituent of Scutellaria(More)
OBJECTIVE To investigate the effect of epirubicin on soluble CD25 (sCD25) secretion by CD4+CD25+ regulatory T (Treg) cells isolated from diffuse large B-cell lymphoma (DLBCL) patients. METHODS Treg cells were isolated from the peripheral blood mononuclear cells isolated from the newly diagnosed DBLCL patients. The concentration of sCD25 in the supernatant(More)
OBJECTIVE To explore the pathological mechanisms of Guizhi Decoction () syndrome and the therapeutic molecular mechanisms of the Guizhi Decoction, Mahuang Decoction (), Sangju Decoction ( ) and Yinqiao Powder (), as well as the potentially biological basis that Guizhi Decoction is most effective only for the patients with Guizhi Decoction syndrome in(More)
OBJECTIVE To investigate the effects of NG-nitro-L-arginine (L-NA) on pulmonary surfactant (PS) and pulmonary cells apoptosis in lipopolysaccharide (LPS) induced acute lung injury (ALI). METHODS Twenty-four male Sprague-Dawley (SD) rats were randomly divided into three groups: control group, model group, L-NA group. Model of ALI was reproduced by(More)
OBJECTIVE To evaluate the role of nimotuzumab in combination with chemotherapy in patients with advanced non-small cell lung cancer (NSCLC). METHODS The clinical data of 37 NSCLC patients who received nimotuzumab in combination with chemotherapy in Tianjin Medical University Cancer Hospital from January 2009 to October 2010 were retrospectively reviewed.(More)
OBJECTIVE The aim of this study was to assess the expression of cell division cycle 7 (Cdc7) kinase and minichromosome maintenance protein 2 (MCM2) in diffuse large B cell lymphoma (DLBCL) and explore their relationship with prognosis of DLBCL patients. METHODS Clinical data of 60 DLBCL patients treated in our hospital from 2008.1 to 2010.1 were(More)