• Publications
  • Influence
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered theExpand
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Role of pro-inflammatory cytokines released from microglia in Alzheimer's disease.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the brain, which is characterized by the formation of extracellular amyloid plaques (or senile plaques) and intracellularExpand
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Microglia in Alzheimer's Disease
Alzheimer's disease (AD) is a familiar neurodegenerative disease in the elderly. In this paper, we will review current viewpoints of microglial activation, inflammatory regulatory systems, and theirExpand
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The prevalence of neuropsychiatric symptoms in Alzheimer's disease: Systematic review and meta-analysis.
BACKGROUND Neuropsychiatric symptoms (NPS) are being increasingly recognized as common serious problems in Alzheimer's disease (AD). However, published data on the prevalence of NPS in persons withExpand
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Epigenetic mechanisms in Alzheimer's disease: Implications for pathogenesis and therapy
The vast majority of Alzheimer's disease (AD) are late-onset forms (LOAD) likely due to the interplay of environmental influences and individual genetic susceptibility. Epigenetic mechanisms,Expand
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Meta-analysis of modifiable risk factors for Alzheimer's disease
  • W. Xu, Lan Tan, +7 authors J. Yu
  • Medicine
  • Journal of Neurology, Neurosurgery & Psychiatry
  • 20 August 2015
Background The aetiology of Alzheimer's disease (AD) is believed to involve environmental exposure and genetic susceptibility. The aim of our present systematic review and meta-analysis was toExpand
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Efficacy and safety of cholinesterase inhibitors and memantine in cognitive impairment in Parkinson's disease, Parkinson's disease dementia, and dementia with Lewy bodies: systematic review with
  • H. Wang, J. Yu, +6 authors Lan Tan
  • Psychology, Medicine
  • Journal of Neurology, Neurosurgery & Psychiatry
  • 14 May 2014
Objective Recently, several large randomised controlled trials about the treatments of cognitive impairment or dementia due to Parkinson's disease (CIND-PD or PDD) and dementia with Lewy bodies (DLB)Expand
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Cognitive Reserve and Alzheimer’s Disease
Alzheimer’s disease (AD), as a neurodegenerative process caused by widespread senile plaques and neurofibrillary tangles, is faced with an increasingly higher incidence as the global aging develops.Expand
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Efficacy and adverse effects of ginkgo biloba for cognitive impairment and dementia: a systematic review and meta-analysis.
BACKGROUND Research into Ginkgo biloba has been ongoing for many years, while the benefit and adverse effects of Ginkgo biloba extract EGb761 for cognitive impairment and dementia has been discussedExpand
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Association between stroke and Alzheimer's disease: systematic review and meta-analysis.
Alzheimer's disease (AD) and stroke are common disorders of aging, but the relationship between these two disorders remains uncertain. Recent evidence recognized that they frequently co-occur and areExpand
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