Lalit Nainiwal

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Hydroxyurea, a myelosuppressive agent, is the only effective drug proven to reduce the frequency of painful episodes. It raises the level of HbF and the haemoglobin level. It usually decreases the rate of painful episodes by 50 %. It was first tested in sickle cell disease in 1984. It also decreases the rate of ACS episodes and blood transfusions by ~50 %(More)
Introduction: Pyoderma gangrenosum (PG) is an idiopathic, ulcerative, non­infective chronic inflammatory skin disorder of unknown etiology rarely affects children. It is associated with systemic medical illness in 50% of cases like inflammatory bowel disease, systemic arthritis, hematological diseases and malignancies. Characteristic lesions begin as(More)
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