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Tumor survival is influenced by interactions between tumor cells and the stromal microenvironment. One example is Endosialin (Tumor Endothelial Marker-1 (TEM-1) or CD248), which is expressedContinue Reading
  • Daniel J O'Shannessy, Mark D Gustavson, Lakshmi Krupa Chandrasekaran, Marisa P. Dolled-Filhart, Elizabeth B. Somers
  • Medicine
  • Biomarkers in medicine
  • 2013 (First Published: 1 December 2013)
  • AIM Although agents that target FRA have advanced through clinical trials, comprehensive analyses of FRA expression in epithelial cancers compared with clinical variables and prognosis are limited.Continue Reading
  • Lakshmi Krupa Chandrasekaran, Jennifer Bordeaux, +7 authors Nagesh Rao
  • Medicine
  • 2014 (First Published: 1 October 2014)
  • HER2 is a prognostic and predictive marker for breast cancer patients and its expression is routinely evaluated by immunochemistry (IHC). Scoring of IHC slides is prone to operator subjectivity andContinue Reading