Lakshmana Pendyala

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Ghrelin, a newly discovered bioactive peptide, is a natural endogenous ligand of the growth hormone (GH) secretagogue receptor and initially identified as a strong stimulant for the release of GH. Subsequent research has shown that ghrelin and its various receptors are ubiquitous in many other organs and tissues. Moreover, they participate in the regulation(More)
OBJECTIVES The present study was designed to delineate and compare the clinical characteristics of patients with apical and non-apical takotsubo syndrome in a high-volume U.S. hospital. BACKGROUND A comparison between apical and non-apical variants of the "broken heart," or takotsubo syndrome, has not been performed in the United States. METHODS From(More)
For my parents, who share my dream. iv ACKNOWLEDGEMENTS The work described herein would have been impossible without significant efforts in the wet side of the McDonald lab from L. as their scientific insights. I would also like to thank my friends on the dry (and sometimes wet) side of the McDonald lab: for their work gathering and interpreting data.(More)
Despite of vast improvements in treatment, myocardial infarction often leads to heart failure (HF) which remains the leading cause of death in developed countries. Other than heart transplantation, therapeutic options have a limited role in improving out comes in patients with severe HF. It is therefore no surprise that cardiac cell therapy has raised many(More)
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