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Silver nanoparticle/chitosan oligosaccharide/poly(vinyl alcohol) nanofibers as wound dressings: a preclinical study
TLDR
The results of the in vitro and in vivo animal experiments suggest that PVA/COS-AgNP nanofibers should be of greater interest than PVA /COS/AgNO3 nan ofibers for clinical use as a bioactive wound dressing.
Efficacy and Safety of Metronidazole Monotherapy versus Vancomycin Monotherapy or Combination Therapy in Patients with Clostridium difficile Infection: A Systematic Review and Meta-Analysis
TLDR
Combination therapy is not superior to monotherapy because it appears to be associated with an increase in the rate of AEs and metronidazole monotherapy is equally effective for the treatment of mild CDI, but vancomycin is superior for the Treatment of severe CDI.
Ascorbyl palmitate-incorporated paclitaxel-loaded composite nanoparticles for synergistic anti-tumoral therapy
TLDR
In vivo, AP/PTX-SLNs were revealed to be much more effective in suppressing tumor growth in B16F10-bearing mice and in eliminating cancer cells in the lungs than single drug (AP or PTX)-loaded SLNs via a synergistic effect through reducing the Bcl-2/Bax ratio.
Zinc oxide/silver bimetallic nanoencapsulated in PVP/PCL nanofibres for improved antibacterial activity
TLDR
The antibacterial effects against Staphylococcus aureus and Escherichia coli of ZnO/Ag/PVP/PCL nanofibres were significantly better than these of the single metal material-loaded nanof fibres in inhibiting growth of bacteria.
A novel electrospun membrane based on moxifloxacin hydrochloride/poly(vinyl alcohol)/sodium alginate for antibacterial wound dressings in practical application
TLDR
The results of the in vitro and in vivo experiments suggest that MH/PVA/SA nanofibers might be an interesting bioactive wound dressing for clinical applications.
Amino Acid Conjugated Anthraquinones from the Marine-Derived Fungus Penicillium sp. SCSIO sof101.
  • M. Luo, Z. Cui, J. Ju
  • Chemistry, Biology
    Journal of natural products
  • 16 May 2017
Emodacidamides A-H (1-8), natural products featuring anthraquinone-amino acid conjugates, have been isolated from a marine-derived fungus, Penicillium sp. SCSIO sof101, together with known
Perioperative Antibiotics to Prevent Acute Endophthalmitis after Ophthalmic Surgery: A Systematic Review and Meta-Analysis
TLDR
This meta-analysis concluded intracameral antibiotics are effective at preventing endophthalmitis in ocular surgery and a randomized controlled trial confirms the efficacy of cefuroxime but recent large cohort studies support the effectiveness of vancomycin/moxifloxacin intracamerally.
Multifunctional Zinc Oxide/Silver Bimetallic Nanomaterial-Loaded Nanofibers for Enhanced Tissue Regeneration and Wound Healing.
  • Mao Li, M. Hu, Y. Ming
  • Materials Science
    Journal of biomedical nanotechnology
  • 1 September 2021
TLDR
In vivo wound healing and histology studies showed that the ZnO/Ag/PVP/PCL nan ofibers had a better anti-inflammatory, skin tissue regeneration, and wound healing effect than monometallic nanofibers or a commercially available wound plaster (Yunnan Baiyao).
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