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  • Laia Capdevila, Sara Cros, +9 authors Carmen Balaña
  • Medicine
  • Journal of Neuro-Oncology
  • 2013 (First Published: 1 March 2014)
  • AbstractPatients with unresectable glioblastoma or anaplastic astrocytoma have a dismal prognosis. The role of neoadjuvant chemotherapy prior to irradiation in these patients has been studiedContinue Reading
  • Juliette Garcia, Cristina Pérez Pérez, Pere Bassa, Laia Capdevila, Francisco Ramos, Vicens Valenti
  • Medicine
  • Clinical nuclear medicine
  • 2017 (First Published: 1 March 2017)
  • In hormone receptor-positive locally advanced breast cancer, endocrine therapy becomes an integral part of the therapeutic strategy. There are now significant numbers of available hormonal directedContinue Reading
  • Daniel E Castellano, Joaquim Bellmunt, +12 authors Joan Carles
  • Medicine
  • Cancer Chemotherapy and Pharmacology
  • 2014 (First Published: 1 April 2014)
  • AbstractPurposeThis exploratory phase II clinical trial evaluated the antitumor activity, safety profile and pharmacokinetics of PM00104 (Zalypsis®) 3 mg/m2 1 h every 3-week intravenous infusion inContinue Reading
    近年来,得益于多种肿瘤分子生物学研究和 有效特异性靶向治疗发展的重大发现,根据患者 基因型的肿瘤个体化治疗已在临床实践中成为可 能[1]。这种基因型特异性抗肿瘤治疗方法有很多, 比如BCR-ABL靶向治疗慢性粒细胞白血病,C-KIT 抑制剂治疗胃肠道间质瘤,KRAS在EGFR抑制剂 无反应的结肠癌中的应用,乳腺癌的HER2导向治 疗以及BRAF抑制剂治疗黑色素瘤[2-13]。其他一些Continue Reading