Learn More
We present an analysis of the first 10 weeks of the severe acute respiratory syndrome (SARS) epidemic in Hong Kong. The epidemic to date has been characterized by two large clusters-initiated by two separate "super-spread" events (SSEs)-and by ongoing community transmission. By fitting a stochastic model to data on 1512 cases, including these clusters, we(More)
BACKGROUND Health authorities worldwide, especially in the Asia Pacific region, are seeking effective public-health interventions in the continuing epidemic of severe acute respiratory syndrome (SARS). We assessed the epidemiology of SARS in Hong Kong. METHODS We included 1425 cases reported up to April 28, 2003. An integrated database was constructed(More)
Joseph T. Wu, Edward S. K. Ma, Cheuk Kwong Lee, Daniel K. W. Chu, Po-Lai Ho, Angela L. Shen, Andrew Ho, Ivan F. N. Hung, Steven Riley, Lai Ming Ho, Che Kit Lin, Thomas Tsang, Su-Vui Lo, Yu-Lung Lau, Gabriel M. Leung, Benjamin J. Cowling, and J. S. Malik Peiris Departments of Community Medicine and School of Public Health, Microbiology, Medicine, and(More)
In Hong Kong, kindergartens and primary schools were closed when local transmission of pandemic (H1N1) 2009 was identified. Secondary schools closed for summer vacation shortly afterwards. By fitting a model of reporting and transmission to case data, we estimated that transmission was reduced approximately 25% when secondary schools closed.
OBJECTIVES Most evidence-based practice (EBP) educational assessment tools evaluated to date have focused on specific knowledge components or technical skills. Other important potential barriers to the adoption of EBP, such as attitudinal, perceptual and behavioural factors, have yet to be studied, especially in the undergraduate setting. Therefore, we(More)
BACKGROUND A variety of Serfling-type statistical algorithms requiring long series of historical data, exclusively from temperate climate zones, have been proposed for automated monitoring of influenza sentinel surveillance data. We evaluated three alternative statistical approaches where alert thresholds are based on recent data in both temperate and(More)
BACKGROUND Timely estimation of the transmissibility of a novel pandemic influenza virus was a public health priority in 2009. METHODS We extended methods for prospective estimation of the effective reproduction number (Rt) over time in an emerging epidemic to allow for reporting delays and repeated importations. We estimated Rt based on case(More)
BACKGROUND In previous literature, the stability and temporal evolution of psychobehavioral responses to an outbreak remained undefined, because of the exclusively cross-sectional nature of such study designs. METHODS Using random-digit dialing, we sampled 4481 Hong Kong residents in 6 population-based surveys that were conducted at different times during(More)
BACKGROUND Accurate and precise estimates of the incubation distribution of novel, emerging infectious diseases are vital to inform public health policy and to parameterize mathematical models. METHODS We discuss and compare different methods of estimating the incubation distribution allowing for interval censoring of exposures, using data from the severe(More)
OBJECTIVE To assess the educational effectiveness on learning evidence based medicine of a handheld computer clinical decision support tool compared with a pocket card containing guidelines and a control. DESIGN Randomised controlled trial. SETTING University of Hong Kong, 2001. PARTICIPANTS 169 fourth year medical students. MAIN OUTCOME MEASURES(More)