Laércio Lima Pilla

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Granulocyte-macrophage colony-stimulating factor (GM-CSF) has been and is still widely used as an adjuvant in clinical trials of vaccination with autologous tumor cells, peptides and/or dendritic cells in a variety of human neoplasms. This cytokine was administered either as product of gene-transduced tumor cells or as recombinant protein together with the(More)
—Multi-core compute nodes with non-uniform memory access (NUMA) are now a common architecture in the assembly of large-scale parallel machines. On these machines, in addition to the network communication costs, the memory access costs within a compute node are also asymmetric. Ignoring this can lead to an increase in the data movement costs. Therefore, to(More)
The High Performance Computing (HPC) community aimed for many years to increase performance regardless of energy consumption. Until the end of the decade, a next generation of HPC systems is expected to reach sustained performances of the order of exaflops. This requires many times more performance compared to the fastest supercomputers of today. Achieving(More)
This work shows how a Hybrid MPI/OpenMP implementation can improve the performance of the Ocean-Land-Atmosphere Model (OLAM) on a multi-core cluster environment , which is a typical HPC many small files work-load application. Previous experiments have shown that the scalability of this application on clusters is limited by the performance of the output(More)
Atmospheric models usually demand high processing power and generate large amounts of data. As the degree of parallelism grows, the I/O operations may become the major impacting factor of their performance. This paper evaluates the Ocean-Land-Atmosphere Model (OLAM) on the PVFS file system in order to point the I/O characteristics of the application. We(More)