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PURPOSE This study evaluated persistent neurosensory deficit (NSD) and functional sensory deficit (FSD) after mandibular bilateral sagittal split osteotomies (BSSO) and their association with patient age at time of operation and eight additional variables. PATIENTS AND METHODS Eighty-five patients more than 2 years post-BSSO were identified and stratified(More)
Fibrous dysplasia (FD) is a non-malignant condition caused by post-zygotic, activating mutations of the GNAS gene that results in inhibition of the differentiation and proliferation of bone-forming stromal cells and leads to the replacement of normal bone and marrow by fibrous tissue and woven bone. The phenotype is variable and may be isolated to a single(More)
PURPOSE The aim of this study was to understand the association of 30 candidate variables with the outcome of mandibular reconstruction. PATIENTS AND METHODS Seventy cases of mandibular reconstruction performed between 1976 and 1991 were identified. Medical records were reviewed for all patients. Thirty variables, including patient factors, preoperative(More)
In this study the mitogenic effect of demineralized bone powder (DBP) on cells in tissue culture was evaluated. The cells studied have osteoblastic properties. At a DBP concentration of 100 micrograms/well, rat osteosarcoma cells (ROS) 17/2.8 cells, ROS 24/1 cells, and periosteal fibroblasts (POF) all showed a significant increase in proliferation in(More)
Although MRI has been reported to be accurate in diagnosing displaced TMJ menisci, it has not been used to characterize the condition of the meniscus. A staging system of internal derangement of the TMJ using MRI signal characteristics and morphology of the meniscus is presented. A normal meniscus has the appearance of a small "drumstick" and is positioned(More)
Previous studies have shown that osteoinduction is inhibited when demineralized bone powder (DBP) is implanted within 48 hours of local irradiation (i.e., when the acute effects of radiation injury are present). This study sought to determine whether normal osteoinduction can proceed if the implantation of DBP is delayed until 21 days postirradiation. At 21(More)
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