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Latent Transforming Growth Factor β-binding Proteins and Fibulins Compete for Fibrillin-1 and Exhibit Exquisite Specificities in Binding Sites*
Latent transforming growth factor (TGF) β-binding proteins (LTBPs) interact with fibrillin-1. This interaction is important for proper sequestration and extracellular control of TGFβ. Surface plasmonExpand
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p38 MAPK Is an Early Determinant of Promiscuous Smad2/3 Signaling in the Aortas of Fibrillin-1 (Fbn1)-null Mice*
Excessive transforming growth factor-β (TGF-β) signaling characterizes the progression of aortic aneurysm in mouse models of Marfan syndrome, a systemic disorder of the connective tissue that isExpand
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A short peptide domain of platelet factor 4 blocks angiogenic key events induced by FGF‐2
Platelet factor 4 (PF‐4) is a CXC‐chemokine with strong anti‐angiogenic properties. We have shown previously that PF‐4 inhibits angiogenesis by associating directly with fibroblast growth factor 2Expand
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Domain swapping in a COOH-terminal fragment of platelet factor 4 generates potent angiogenesis inhibitors.
A few peptide residues in structurally important locations often determine biological functions of proteins implicated in the regulation of angiogenesis. We have shown recently that the shortExpand
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Structure and Inhibitory Effects on Angiogenesis and Tumor Development of a New Vascular Endothelial Growth Inhibitor*
Blocking angiogenesis is an attractive strategy to inhibit tumor growth, invasion, and metastasis. We describe here the structure and the biological action of a new cyclic peptide derived fromExpand
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Solution Structure and Interaction with Basic and Acidic Fibroblast Growth Factor of a 3-kDa Human Platelet Factor-4 Fragment with Antiangiogenic Activity* 210
Platelet factor-4 is a protein belonging to the family of ELR-negative CXC chemokines which binds to fibroblast growth factor and inhibits its mitogenic activity. Platelet factor-4 also inhibitsExpand
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Effect of distal hamstring release on cerebral palsy patients.
Thirty patients had distal hamstring release with modified Green technique: 21 spastic diplegics, 8 spastic quadriplegics, and 1 spastic hemiplegic. The average age at the time of surgery was 6.9Expand
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[Medical support for the landing in the Eltigen area in 1943].
The authors have used archive data to show the peculiarities of medical support of naval landing of troops at the region of Eltigen. The 279-th medical battalion immediately after landing was underExpand
Identification et caractérisation de peptides inhibiteurs de l'angiogenèse
L'angiogenese est la croissance de nouveaux vaisseaux a partir de vaisseaux preexistants. L'angiogenese est observee dans des pathologies telles que le cancer, la retinopathie du diabete et lesExpand